American Venom is a main story mission in Red Dead Redemption 2 given by Sadie Adler, as part of Epilogue - Part 2.
This is the final mission and ending of the storyline of Red Dead Redemption 2, played with protagonist John Marston.
American Venom - Mission Details:
Sadie has a clue that might lead them to Micah - Cleet has been sighted in Strawberry. Despite Abigail's protests, John, Sadie and Charles ride there to interrogate him and track down their old enemy.
Mission Objectives
Gold Medal Objectives (100%)
The following are the Mission Objectives required to obtain the Gold Medal in the mission "American Venom":
- Help Sadie catch Cleet within 35 seconds
- Headshot the sniper who shoots Charles
- Complete with at least 85% accuracy
- Complete the mission without taking any health items
Note: You must complete all Gold Medal requirements in one single playthrough of the mission.
American Venom: Mission Info
- Mission Number 110
- Story Chapter Epilogue - Part 2
- Mission Giver
Sadie Adler - Mission Type Mandatory Mission
- Protagonist (Playable)
John Marston - Location From Beecher's Hope (Great Plains, West Elizabeth), to Strawberry (Big Valley, West Elizabeth), to Mount Hagen (Grizzlies West, Ambarino)
- Rewards $20,000.00
- Unlocked Items
Micah's Revolver - Featuring
Micah's Revolver
Abigail Roberts (Marston) 
Charles Smith 
Cleet 
Dutch van der Linde 
Joe 
Micah Bell Sadie Adler - Notes Final Story Mission of Red Dead Redemption 2.